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Magnesium
Helps nerve and muscle function†
Benefits
  • Helps regulate heart function
  • Helps the body maintain a healthy blood pressure
  • Magnesium helps the body produce energy
Precautions
  • A high calcium and vitamin D intake could result in decreased magnesium absorption. Other drugs effecting magnesium status are diuretics, insulin and digitalis.
  • People with kidney disease or severe heart disease should not take magnesium unless prescribed by healthcare provider.
Drug Nutrient Interactions
Recommended Icon
Antihypertensive Drugs (Diuretics)

Thiazide diuretics can increase magnesium loss and reduce serum levels. This is more likely to occur with higher diuretic doses or when used in combinations with other antihypertensive drugs.Consult with healthcare provider regarding appropriate magnesium supplementation, necessary labs and monitoring schedule.
RX recommended Icon
Current research does not indicate that this supplement provides additional therapeutic benefit's when taking any of the drug categories included in this table.
Caution icon
Antibiotics

Magnesium forms insoluble complexes with tetracycline and fluoroquinolone antibiotics and can diminish absorption of both the antibiotic and the mineral when taken concomitantly. Advise patients to take tetracyclines or fluoroquinolones at least 2 hours before, or four to six hours after magnesium supplements.
Osteoporosis Medications

Divalent cations (eg calcium, iron, etc) can significantly decrease the oral bioavailability of the bisphosphonates (Fosamax, Actonel, Boniva) if taken concurrently. Caution patients not to take iron supplements for at least one to two hours after their bisphosphonate medication.
Avoid icon
Current research does not indicate that this supplement should be avoided when taking any of the drug categories included in this table.
 Nutrition and Health State
RX recommended Icon
If no prescription medications are being used, the following supplements may be beneficial for this health state. If prescription medications are being used, please see the drug-interaction database before making recommendations.
A daily multivitamin will help ensure adequate intake of all essential nutrients and promote overall health and well-being.
PMS

200-400 mg/day. Magnesium may help in alleviating PMS symptoms.
Hypertension (high blood pressure)

Magnesium supplementation may help improve blood flow and maintain healthy blood pressure levels.
Headache/Migraine

Magnesium supplements alone or combined with B2 and feverfew may reduce the recurrence rate and severity of migraines.
Dysmenorrhea

300 mg/day. Preliminary studies suggest that magnesium supplementation may be helpful for dysmenorrhea by improving symptoms.
PMS

200-400mg/day. Magnesium may help in alleviating PMS symptoms.
Caution icon

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