Caution with pregnancy or nursing, consult physician before using.
Information on the relationship between substances and disease is provided for general information, in order to convey a balanced review of the scientific literature. In many cases the relationship between a substance and a disease is tentative and additional research is needed to confirm such a relationship.
Ocular disorders: The most recent study, by Muth and colleagues, investigated the effects of bilberry on night visual acuity and night contrast sensitivity. The trial was of a randomized, double blind, placebo-controlled, crossover design. Two groups of healthy men with good vision each received either bilberry extract standardized to 25% anthocyanosides (160 mg 3 times daily) or placebo for 21 days. The results failed to find an effect of bilberry on night visual acuity or night contrast sensitivity for this population. However, all of the trials, conducted in 1998 5, 1999 6 and 2000 4, were on healthy males with good vision, of ages ranging from 21 to 47 years.
On the other hand, remarkable success has been achieved in treatment of vascular retinopathy; 77% to 90% improvement was observed in a one-month double-blind placebo-controlled crossover study involvint 40 outpatients diagnosed with diabetes and/or hypertension 7.
Diabetic cataracts are caused by an elevation of polyols within the lens of the eye catalyzed by the enzyme aldose reductase. Flavonoids, particularly quercetin and its derivatives, which are found in bilberry, as well as in other fruits, are potent inhibitors of aldose reductase. Head 8 suggested that botanicals such as bilberry may play a role in cataract prevention.
Anti-diabetic:Animal studies suggest that bilberry leaves (rather than fruit) may be helpful for improving blood glucose control in diabetes and lowering serum triglyceride concentrations. 9 The chromium content is thought to be responsible for the antidiabetic effect.
The dietary supplement information contained on this site has been compiled from published sources thought to be reliable, but it cannot be guaranteed. Efforts have been made to assure this information is accurate and current. However, some of this information may be purported or outdated due to ongoing research or discoveries. The authors, editors and publishers cannot accept responsibility for errors or omissions or for any consequences from applications of the information in this site and make no warranty, expressed or implied, with respect to the contents herein.